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8th Annual Early Alzheimer's Disease (formerly MCI) Symposium, 2010
Focus on Early and Preclinical Alzheimer's Disease
(March 12th and March 13th, 2010, at the Eden Roc Hotel, Miami Beach)
FRIDAY, MARCH 12, 2010
Morning
7:00am to 8:00am - Breakfast Buffet
8:00am to 8:15am - Welcome and Introduction (Ranjan Duara, MD)
8:15am to 9:00am - Keynote Address: Rationale for a PreClinical AD Diagnosis (John Morris, MD)
9:00am to 10:30am - Mini-Symposium: PreClinical AD: Longitudinal Studies (Chair: Ron Petersen, MD, PhD)
1. The Preclinical Phase of Alzheimer's Disease: A 20 Year Prospective Study of the Framingham Cohort - Rhoda Au, PhD

2. Longitudinal Cognitive Changes in PreMCI states: Effect of Clinical, Imaging and Genetic Factors - Richard Caselli, MD

3. 2-4 Year Outcome of PreMCI States in the Florida ADRC - David Loewenstein, PhD
10:30am to 11:00am - Open Discussion
11:00am to 11:15pm - Break
11:15am to 12:30pm - Mini-Symposium: Clinical Trials and Genetics of AD (Chair: Eric Siemers, MD)
1. Enriching Future Prevention Trials with Genetic Risk Assessment and Disclosure - Robert C. Green, MD, MPH

2. Significance of the MIDAS and ADCS Trials with DHA for Secondary Prevention and Treatment of AD - Joseph Quinn, MD

3. The Future of Clinical Trials for Treatment and Prevention of AD - Eric Siemers, MD
12:30am to 1:15pm - Open Discussion
Afternoon
1:15pm to 2:30pm - Lunch
2:30pm to 4:15pm - Mini-Symposium: Biomarkers for Early AD, MCI and PreMCI (Chair: Steven DeKosky, MD)
1. FDG-PET Imaging in the Evaluation of Very Early AD: Contributions of the Alzheimer's Disease Neuroimaging Initiative (ADNI) - Norman Foster, MD

2. Amyloid Imaging and fMRI studies in Early AD
- Reisa Sperling, MD

3. Cerebral Glucose Metabolism in PreClinical AD with Maternal Family History of AD
- Lisa Mosconi, PhD
4:15pm to 5pm - Open Discussion
SATURDAY, MARCH 13, 2010
Morning
7:30am to 8:30am - Breakfast Buffet
8:30am to 9:15am - Keynote Address: Amnestic and Non-amnestic MCI are Distinct Entities? Fact or Fiction? (Mark Bondi, PhD)
9:15am to 9:30am - Break
9:30am to 11:30am - Mini-Symposium: Challenges in Interpreting Psychometric Test Results in Early AD, MCI and PreMCI (Chair: Mary Ganguli, MD)
1. PreMCI, Alzheimer's Disease and Cognitive Reserve
- Catherine Roe, PhD

2. Verbal Fluency and Executive Function in MCI and Subjects with Cognitive Complaints
- Katherine Nutter-Upham, MA

3. Quantification of Neuropsychological Approaches to Defining MCI Subtypes
- Amy Jak, PhD

4. Assessment of Cognitive Impairment in Minority Populations - Jennifer Manly, PhD
11:30am to 11:45am - Break
11:45am to 12:30pm - Open Discussion
Adjourn
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